分子别名（Synonym）:gp140

种属（Species）：HIV

表达系统（Expressed Host）：HEK293 Cells

产品状态（Buffer）：Lyophilized from sterile PBS, pH 7.4

分子量（Molecule Mass）：The recombinant HIV-1 gp140 consists of 874 amino acids after removal of the signal peptide and has a predicted molecular mass of 98 kDa. The apparent molecular mass of the recombinant protein is approximately 210-230 kDa in SDS-PAGE under reducing conditions.

内毒素（Endotoxin）：＜1.0 EU per μg by the LAL method.

生物活性(Activity)：Using the Octet RED System, the affinity constant (Kd) of gp140-Fc bound to human CD4 is 0.3 μM.

表达区间（Protein Construction）：A DNA sequence encoding the HIV-1 envelope glycoprotein gp160 extracellular domain (Ala 29-Ser 661), termed as gp140, was fused with the Fc region of human IgG1 at the C-terminus and a signal peptide at the N-terminus.

存储条件（Storage）： For long term storage, the product should be stored at lyophilized state at -20℃ or lower.Please avoid repeated freeze-thaw cycles. No activity loss is observed after storage at:4-8℃ for 12 months in lyophilized state;-70℃ for 3 months under sterile conditions after reconstitution.

运输条件： In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.