分子别名(Synonym):4930516B21Rik,ActRIIB
种属(Species):Mouse
表达系统(Expressed Host):HEK293 Cells
产品状态(Buffer):Lyophilized from sterile PBS, pH 7.4
分子量(Molecule Mass):The recombinant mouse ACTRIIB/ACVR2B comprises 127 amino acids and has a predicted molecular mass of 14.8 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmACVR2B is approximately 33-37 kDa due to glycosylation.
内毒素(Endotoxin):<1.0 EU per μg by the LAL method.
生物活性(Activity):1. Measured by its binding ability in a functional ELISA. Immobilized human ACVR2B (Cat:H1453-202H) at 10 μg/mL (100 μl/well) can bind biotinylated mouse INHBA-His (Cat:M1883-802H), The EC50 of biotinylated mouse INHBA-His (Cat:M1248-802H) is 0.161 μg/mL.
表达区间(Protein Construction):A DNA sequence encoding the extracellular domain of mouse ACTRIIB (NP_031423.1) (Ser 2-Thr 134) was fused with a polyhistidine tag at the C-terminus.
存储条件(Storage): For long term storage, the product should be stored at lyophilized state at -20℃ or lower.Please avoid repeated freeze-thaw cycles. No activity loss is observed after storage at:4-8℃ for 12 months in lyophilized state;-70℃ for 3 months under sterile conditions after reconstitution.
运输条件: In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
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