分子别名（Synonym）:Noggin,SYM1,SYNS1
 

种属（Species）：Human
 

表达系统（Expressed Host）：HEK293 Cells
 

产品状态（Buffer）：Lyophilized from sterile 100mM Glycine, 10mM NaCl, 50mM Tris, pH 7.5
 

分子量（Molecule Mass）：The recombinant human Noggin/Fc is a disulfide-linked homodimeric protein after removal of the signal peptide. Each monomer comprises 443 amino acids and has a predicted molecular mass of 49.8 kDa. As a result of glycosylation, the apparent molecular mass of rhNoggin/Fc monomer is approximately 58-62 kDa in SDS-PAGE under reducing conditions.
 

内毒素（Endotoxin）：＜1.0 EU per μg by the LAL method.
 

生物活性(Activity)：1. Measured by its ability to inhibit BMP2-induced alkaline phosphatase production by MC3T3-E1 cells.
 

表达区间（Protein Construction）：A DNA sequence encoding the human Noggin precursor (NP_005441.1) (Ser 2-Cys 232) was fused with the Fc region of human IgG1 at the C-terminus.
 

存储条件（Storage）：For long term storage, the product should be stored at lyophilized state at -20℃ or lower.Please avoid repeated freeze-thaw cycles. No activity loss is observed after storage at:4-8℃ for 12 months in lyophilized state;-70℃ for 3 months under sterile conditions after reconstitution.  

运输条件：In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.