分子别名(Synonym):ACTRI,ACVR1A,ACVRLK2,ALK2,FOP,SKR1,TSRI
种属(Species):Human
表达系统(Expressed Host):HEK293 Cells
产品状态(Buffer):Lyophilized from sterile PBS, pH 7.4
分子量(Molecule Mass):The recombinant human ALK2/Fc is a disulfide-linked homodimeric Protein after removal of the signal peptide. Each monomer consists of 352 amino acids and predicts a molecular mass of 39.6 kDa. As a result of glycosylation, the rh ALK2/Fc monomer migrates as approximately 40-45 kDa band in SDS-PAGE under reducing conditions.
内毒素(Endotoxin):<1.0 EU per μg by the LAL method.
生物活性(Activity):Measure by its ability to bind with human BMP2 in a functional ELISA.
表达区间(Protein Construction):A DNA sequence encoding the extracellular domain (Ser 2-Val 124) of human ALK2 (NP_001104537.1) precursor was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
存储条件(Storage): For long term storage, the product should be stored at lyophilized state at -20℃ or lower.Please avoid repeated freeze-thaw cycles. No activity loss is observed after storage at:4-8℃ for 12 months in lyophilized state;-70℃ for 3 months under sterile conditions after reconstitution.
运输条件: In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
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