分子别名（Synonym）:CD120a,FPF,MS5,p55,p55-R,p60,TBP1,TNF-R,TNF-R-I,TNF-R55,TNFAR,TNFR1,TNFR1-d2,TNFR55,TNFR60

种属（Species）：Human

表达系统（Expressed Host）：HEK293 Cells

产品状态（Buffer）：Lyophilized from sterile PBS, pH 7.4

分子量（Molecule Mass）：The recombinant human TNFRI/Fc is a disulfide-linked homodimer. The reduced monomer consists of 438 amino acids and has a predicted molecular mass of 49.3 kDa. As a result of glycosylation, rh TNFRI/Fc monomer migrates with an apparent molecular mass of 60-65 kDa in SDS-PAGE under reducing conditions.

内毒素（Endotoxin）：＜1.0 EU per μg by the LAL method.

生物活性(Activity)：Measured by its ability to inhibit TNF-α-mediated cytotoxicity in L-929 mouse fibrosarcoma cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is typically 2-12ng/mL in the presence of 1 ng/mL recombinant human TNF-α.

表达区间（Protein Construction）：A DNA sequence encoding the human TNFRI (NP_001056.1) extracellular domain (Ser 2-Thr 211) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.

存储条件（Storage）： For long term storage, the product should be stored at lyophilized state at -20℃ or lower.Please avoid repeated freeze-thaw cycles. No activity loss is observed after storage at:4-8℃ for 12 months in lyophilized state;-70℃ for 3 months under sterile conditions after reconstitution.

运输条件： In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.